Weekly Digest
Weekly ToC Digest (week of 2026-08-10)
No items directly related to brain-aging or neuroimaging-based aging models this week. Focus on neuroimaging, brain age prediction, and computational methods in brain aging. No highly relevant brain-aging model papers found this week. Articles focus more on general neuroscience and do not align with user’s computational modeling interests in brain age prediction and normative modeling. Focused on brain-aging models and computational methodologies, selected relevant articles based on user interests in neuroimaging, brain age modeling, and computational techniques.
Included: 5 (score ≥ 0.35)
Scored: 10 total items
Boosting hyperalignment performance with age-specific templates
eLife
Score: 0.90
Published: 2026-08-05T00:00:00+00:00 Tags: brain age, MRI, normative
The article addresses age-specific brain functional changes and alignment through computational models, relevant for brain-age modeling.
RSS summary
Hyperalignment aligns individual brain activity and functional connectivity patterns to a common, high-dimensional model space, resolving idiosyncrasies in functional–anatomical correspondence and revealing shared information encoded in fine-grained spatial patterns. Given that the brain undergoes significant developmental and functional changes over the lifespan, certain features in brain functional organization may be more prominent in certain age groups than others. In this study, we examined…
Premature epigenetic aging, deviations from normative brain development, and cognitive performance in young adulthood
Trans Psychiatry
Score: 0.70
Published: 2026-08-06T00:00:00+00:00 Tags: epigenetic aging, normative, cognition
Mentions epigenetic aging and deviations from normative brain development, aligning with interests in brain age and normative models.
RSS summary
Translational Psychiatry, Published online: 06 August 2026; doi:10.1038/s41398-026-04337-3
Premature epigenetic aging, deviations from normative brain development, and cognitive performance in young adulthood
Efficient and reproducible pipelines for spike sorting large-scale electrophysiology data
eLife
Score: 0.60
Published: 2026-08-05T00:00:00+00:00 Tags: computational, pipelines, efficiency
Involves computational/pipeline development, which is crucial for aging-related computational neuroscience although not directly brain-age focused.
RSS summary
The scale of in vivo electrophysiology has expanded in recent years, with simultaneous recordings across thousands of electrodes now becoming routine. These advances have enabled a wide range of discoveries, but they also impose substantial computational demands. Spike sorting, the procedure that extracts spikes from extracellular voltage measurements, remains a major bottleneck: a dataset collected in a few hours can take days to spike sort on a single machine, and the field lacks rigoro…
Multimodal neuroimaging-microbiota integration identifies Akkermansia as a modulator of alcohol-induced gut-liver-brain pathology
bioRxiv
Score: 0.50
Published: 2026-08-07T00:00:00+00:00 Tags: multimodal, MRI, brain pathology
This study integrates advanced diffusion MRI with microbiota profiling to investigate the gut-brain axis, which may provide insights into brain aging mechanisms.
RSS summary
Alcohol use disorder (AUD) disrupts the gut-liver-brain axis, yet mechanistically grounded and therapeutically actionable targets within this network remain poorly defined. To identify microbial modulators of alcohol-induced tissue pathology, longitudinal advanced diffusion MRI and fecal 16S rRNA profiling were integrated across Marchigian Sardinian alcohol-preferring rats evaluated at baseline, after four weeks of voluntary alcohol intake, and following six weeks of abstinence. Machine learning…
Social inequalities linked to accelerated biological aging
Nature Aging
Score: 0.50
Published: 2026-08-06T00:00:00+00:00 Tags: biological aging, social factors
Addresses accelerated biological aging but lacks a direct focus on computational brain-age models or neuroimaging contributions.
RSS summary
Nature Aging, Published online: 06 August 2026; doi:10.1038/s43587-026-01201-3
Social inequalities linked to accelerated biological aging